BRN 0114548
8-fluoroquinoline
CAS: 394-68-3
Molecular Formula: C9H6FN
BRN 0114548 - Names and Identifiers
| Name | 8-fluoroquinoline |
| Synonyms | CCRIS 2891 BRN 0114548 8-Fluoroquinoine 8-FLUOROQUINOLINE 8-fluoroquinoline 8-fluoro-quinolin Quinoline, 8-fluoro- |
| CAS | 394-68-3 |
| EINECS | 807-825-2 |
| InChI | InChI=1/C9H6FN/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H |
BRN 0114548 - Physico-chemical Properties
| Molecular Formula | C9H6FN |
| Molar Mass | 147.15 |
| Density | 1.215 g/cm3(Temp: 25 °C) |
| Boling Point | 148 °C(Press: 30 Torr) |
| Flash Point | 98°C |
| Vapor Presure | 0.0654mmHg at 25°C |
| Appearance | clear liquid |
| Color | Colorless to Light yellow to Light orange |
| pKa | 1.93±0.17(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.60 |
BRN 0114548 - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
BRN 0114548 - Introduction
8-fluoroquinoline is an organic compound with the chemical formula C9H5FN, which is a derivative of quinoline. The following is a description of the properties, uses, formulation and safety information of 8-fluoroquinoline:
Nature:
- 8-fluoroquinoline is a colorless to pale yellow solid.
-It is stable at room temperature and can be dissolved in organic solvents such as alcohols and ketones.
-It has the characteristics of quinoline compounds, including aromatic rings and nitrogen-containing heterocyclic structures.
Use:
- 8-fluoroquinoline has a wide range of applications in the field of medicine. It is an important organic synthesis intermediate, which can be used to synthesize various drugs.
-It has antibacterial activity against a variety of bacteria and fungi, so it can be used as a raw material for antibiotics and antifungal drugs.
Preparation Method:
-The method for preparing 8-fluoroquinoline is usually obtained by reacting quinoline with fluorine gas under appropriate conditions.
-This reaction needs to be carried out in an organic solvent containing a catalyst, such as tetrahydrofuran.
Safety Information:
- 8-fluoroquinoline is an organic compound that requires careful handling. Pay attention to the following safety precautions during use and storage:
-Avoid contact with skin, eyes and respiratory tract. Wear protective gloves, goggles and protective masks when using.
-The operation should be carried out in a well-ventilated place.
-When storing, keep it in a sealed container, away from heat sources and open flames.
-Waste should be disposed of in accordance with local regulations.
Nature:
- 8-fluoroquinoline is a colorless to pale yellow solid.
-It is stable at room temperature and can be dissolved in organic solvents such as alcohols and ketones.
-It has the characteristics of quinoline compounds, including aromatic rings and nitrogen-containing heterocyclic structures.
Use:
- 8-fluoroquinoline has a wide range of applications in the field of medicine. It is an important organic synthesis intermediate, which can be used to synthesize various drugs.
-It has antibacterial activity against a variety of bacteria and fungi, so it can be used as a raw material for antibiotics and antifungal drugs.
Preparation Method:
-The method for preparing 8-fluoroquinoline is usually obtained by reacting quinoline with fluorine gas under appropriate conditions.
-This reaction needs to be carried out in an organic solvent containing a catalyst, such as tetrahydrofuran.
Safety Information:
- 8-fluoroquinoline is an organic compound that requires careful handling. Pay attention to the following safety precautions during use and storage:
-Avoid contact with skin, eyes and respiratory tract. Wear protective gloves, goggles and protective masks when using.
-The operation should be carried out in a well-ventilated place.
-When storing, keep it in a sealed container, away from heat sources and open flames.
-Waste should be disposed of in accordance with local regulations.
Last Update：2024-04-09 02:00:45
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CAS: 394-68-3
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Product Name: 8-FLUOROQUINOLINE Visit Supplier Webpage Request for quotation
CAS: 394-68-3
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CAS: 394-68-3
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